Hemoglobinuria

How to Differentiate Hemoglobinuria with Hematuria and Myoglobinuria???

Hemoglobinuria - *Presence of Hemoglobin in the urine 

                              *It is due to the lysis of RBC ( Intravascular Hemolysis) 

                              * RBC are destroyed and released hemoglobin in the plasma which in time filtered                                       by kidney as dark brown in color or coffee colored urine

Hematuria - Presence of Blood in Urine

Myoglobinuria _ presence of Myoglobin in urine

To differentiate Hemoglobinura and Hematuria 

  Centrifuge the urine sample 

  If Hemoglobinuria there wont be any colur changes after centrifuge

 If hematuria RBC will settle down and clear urine will be separated  

To Differentiate hemoglobinuria and Myoglobinuria

   Evaluate the Plasma color

   Hemoglobinuria will have pink to red plasma colur

   Myoglobinuria will not have pink to red colur plasma

But in Urine dip stick analysis all the above three will show positive for blood .